Repair of penile urethral strictures is a challenging problem for which different techniques have been suggested.
To describe a new surgical technique for one-stage penile urethroplasty using an oral graft and glue, and to assess its safety and efficacy.
Design, setting, and participants
A retrospective review of medical records for patients who underwent one-stage penile urethroplasty using oral mucosa and glue from February 2013 to October 2014 was performed.
The penile urethra was opened and the urethral plate was incised to create a wide window within which the oral graft was pasted with glue. The urethra was sutured over the catheter.
Outcome measurements and statistical analysis
Clinical data were collected in a database. Intraoperative and postoperative complications and outcomes were assessed. A descriptive statistical analysis was performed.
Results and limitations
Fourteen patients were included in the study. Median operative time was 60 min. The median postoperative stay was 3 d. Three intraoperative and one postoperative complication occurred. In all patients, voiding cystourethrography 2 wk after surgery failed to show urethral fistula or sacculation. No patients complained of penile chordee or sexual dysfunction after surgery. Median follow-up was 16 mo. Among the 14 patients, 12 (85.7%) procedures were successful and two (14.3%) were failures. Study limitations include the small sample size and short follow-up.
An in vitro study and a one-stage reconstruction of penile urethral strictures with an oral mucosa graft and glue showed that the procedure is safe and efficient, but further studies including larger series of patients and longer follow-up are required.
We report on the repair of penile urethral stricture using one-stage urethroplasty with oral mucosa and glue. This new technique was safe and effective, with limited complications and satisfactory outcomes. We plan to increase the use of this technique in the future.
Keywords: Penile stricture, One-stage urethroplasty, Oral mucosal graft, Glue.
a Centro Chirurgico Toscano, Arezzo, Italy
b Centre for Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy
c Division of Oncology, Unit of Urology, IRCCS Ospedale San Raffaele, Milan, Italy
d Department of Experimental Medicine and Surgery, University of Tor Vergata, Rome, Italy
e Research Institute for Uronephrology, Sechenov First Moscow State Medical University, Moscow, Russia
f Department of Urology, Istituto Clinico Humanitas IRCCS, Clinical and Research Center, Rozzano, Italy
Corresponding author. Department of Urology, Istituto Clinico Humanitas IRCCS, Clinical and Research Center, via Manzoni 56, 20089 Rozzano, Milan, Italy. Tel. +39 02 82244545.
© 2016 European Association of Urology, Published by Elsevier B.V.